Immerse yourself in the charms of old-world Firenze. The birthplace and focal point of the Italian Renaissance, Florence still has the masterpieces to prove it. Brunelleschi’s monumental cupola (dome) atop the city's renowned Duomo dominates the skyline. Your local licensed guide will take you to Giotto's Bell Tower and the aptly named Gates of Paradise, the bronze east doors of the Baptistery that spurred the burgeoning Renaissance. Don’t overlook the tombs of Michelangelo, Galileo, and Machiavelli at the Chiesa di Santa Croce, or Florence’s amazing leather goods. You can check them out when you visit one of the area’s famed workshops!

Spend time in the Piazza della Signoria, the political stage of Renaissance Florence and an open-air museum of sculpture.

Stroll along the Ponte Vecchio, the oldest of Florence's six bridges and one of the best-loved sites of Florence. Lined with numerous shops, visitors often do not realize they are on a bridge until the reach the center arches that look out over the Arno.

In fair Verona shall we lay our scene. The setting for Shakespeare’s “Romeo and Juliet” still glows with romance. See Juliet’s balcony, tenderly draped with climbing ivy and overlooking a golden-hued statue of the young mistress herself. As you gaze out and contemplate the power of love, don’t get too swept away -- remember that while Shakespeare based his characters on Verona’s real-life feuding families, both Romeo and Juliet were, in fact, fictional.

Brush up on your Shakespeare before visiting Casa di Giulietta, where you can look up at the balcony long associated with the story of Romeo and Juliet. Learn how many versions of this tragic tale existed well before Shakespeare gave it its most famous form. From this legendary setting of star-crossed love, continue on to Verona’s Roman Arena, a remarkably preserved 1st-century B.C. amphitheater. Still used for performances today, it is the third-largest arena of its kind in Italy.

Bubbling up on more than 100 islands in a lagoon off the Adriatic, Venice is an absolutely unique and unquestionably beautiful city. Step into Piazza San Marco, an airy expanse of arches, sunlight, and pigeons. The multi-domed Basilica on one end, completed in 1094 but decorated for centuries afterward, is the final resting place of the apostle St. Mark, Venice’s patron saint. The mosaics beneath the basilica’s outside arches depict the arrival of St. Mark’s body, stolen from Egypt in 828 by Venetian traders. The frothy Venetian Gothic Doge’s Palace stands next door. Continue on to a glass-blowing demonstration. Venetian glass has long been considered the best in the world, and its production was such a state secret that during the Middle Ages, any Venetian glassblower who attempted to ply his trade outside the city was immediately arrested.

Stroll through St. Mark's Square. Bordered by Venice's greatest historic buildings, St. Mark's Square is the center of both the city and its water transportation system, as well as a popular tourist attraction.

Discover the Doge’s Palace, once the seat of government and justice in the Venetian Republic. Its lavish rooms, monumental artwork, and intricate architectural details reveal the wealth and influence that defined Venice at its height.

A small town of narrow streets and medieval walls, Assisi might never have been famous had it not been the birthplace of St. Francis, the founder of the Franciscan order. Today it is a major destination for religious pilgrims and art lovers alike. You’ll explore the Basilica of St. Francis, built in the 13th century to hold the saint’s body. Ironically, the body was hidden so well in the basilica that it took 600 years of digging to find it.

The Basilica of St. Francis of Assisi is one of Italy’s most important pilgrimage sites, built soon after the saint’s canonization in the early 13th century. The complex includes both a Lower Basilica, created as a space for prayer and devotion, and an Upper Basilica, known for its early and influential fresco cycles. Together, these two churches form a UNESCO World Heritage Site and stand as a major landmark of medieval spirituality, architecture, and art.

The ultimate symbol of Ancient Rome, the Colosseum still dominates the modern city. Tour the amphitheatre with your local licensed guide. Built by the emperor Vespasian in A.D. 72, the structure held almost 50,000 spectators but was so well organized that the entire place could be emptied within 15 minutes. Inside, the spectacles varied from gladiator battles to immense naval contests to wild beast shows, in which thousands of exotic animals like giraffes and ostriches were popped into the stadium through trap doors and left to fight Roman hunters. See the system beneath the floor that operated the trap doors and housed the animals, then continue on to the relative calm of the Forum. Ancient Rome’s commercial, religious and political center, the Forum held markets, temples and the Senate House. Near the Rostra, or speaker’s platform, you can still see game boards scratched into the marble by bored politicians--anyone up for a game of tic tac toe?

Tour the ruins and excavations of the Roman Forum, which features the remains of magnificent temples, basilicas, and triumphal arches that once formed the heart of the Empire.

Visit St. Peter’s Basilica, with its vast colonnades that seem to embrace the world. Inside, admire Michelangelo’s soaring dome, rising 452 feet above the ground, and his renowned Pietà. Then step into the Sistine Chapel, where the artist reluctantly painted frescoes that today stand among the world’s greatest masterpieces. Please note that the Sistine Chapel portion of the visit is unguided and will be explored independently.

Take a walk past Rome's most beautiful and unusual Baroque fountains. At the foot of the Spanish Steps, elegant cafes surround the central fountain. The water pressure here was so low that the artist had to sink the fountain into the ground to get any water going through it, so he went ahead and designed the fountain to look like a sinking ship. There's no shortage of water pressure at the nearby Trevi Fountain, a Baroque extravagance designed by master sculptor Bernini.

View the Trevi Fountain, where it is traditional to toss a coin into the fountain to ensure a safe return to the Eternal City.

We will spend some time in the Piazza Navona area. Built on the foundations of Domitian's Circus, this magnificent square was designed by Borromini in 17th century. It is full of life and is highlighted by one of Rome's most spectacular fountains, the Four Rivers designed by Bernini. The square is often filled with local artists. The surrounding neighborhood is also one of the best places in Rome to get a tasty tartufo or gelato ice cream